Main areas of research

I'm involved in a wide variety of research. These can be roughly grouped as follows:

  • 3D microscopy image visualisation and analysis
  • Virtual Reality applications
  • Machine learning with a focus on deep neural networks applied to image processing problems
    • Human Pose-Estimation
    • Face Recognition
  • Internet of Things (IoT) applications

Publications

ORCID
Google Scholar
Scopus

Journal Publications

# Paper Print (DOI) Pre-P (Open) Data/
Video
12 de Wet S, Theart R, Loos B. Cogs in the autophagic machine—equipped to combat dementia-prone neurodegenerative diseases. Frontiers in Molecular Neuroscience. 2023 Aug 31. Link
11 Buchanan E, Mahony C, Bam S, Jaffer M, Macleod S, Mangali A, van der Watt M, de Wet S, Theart R, Jacobs C, Loos B. Propionic acid induces alterations in mitochondrial morphology and dynamics in SH-SY5Y cells. Scientific Reports. 2023 Aug 15;13(1):13248. Link
10 de Wet S, Mangali A, Batt R, Kriel J, Vahrmeijer N, Niehaus D, Theart R, Loos B. The Highs and Lows of Memantine—An Autophagy and Mitophagy Inducing Agent That Protects Mitochondria. Cells. 2023 Jun 27;12(13):1726. Link
9 Muthua AG, Theart RP, Booysen MJ. Using infrared to improve face recognition of individuals with highly pigmented skin. iScience. 2023 Jun 8. Link Link
8 Biggs DR, Theart RP, Schreve K. Improving object counting in aerial images with density-based threshold shifting. International Journal of Remote Sensing. 2023 May 26:1-8. Link Link
7 De Villiers JG, Theart RP Predicting mitochondrial fission, fusion and depolarisation event locations from a single z-stack. PLoS ONE 8 Mar 2023;18(3): e0271151. Link Link Link
6 Robertson GL, Riffle S, Patel M, Bodnya C, Marshall A, Beasley HK, Garza-Lopez E, Shao J, Vue Z, Hinton Jr A, Stoll MS, De Wet S, Theart RP, Chakrabarty RP, Loos B, Chandel N, Mears J, Gama V. DRP1 mutations associated with EMPF1 encephalopathy alter mitochondrial membrane potential and metabolic programs. Journal of Cell Science. 2023 Feb 1;136(3):jcs260370. Link Link
5 Theart RP, Kriel J, du Toit A, Loos B, Niesler TR. Mitochondrial event localiser (MEL) to quantitatively describe fission, fusion and depolarisation in three-dimensional space. Plos ONE. 2020 Dec 30;15(12):e0229634. Link Link Link
4 Theart RP, Loos B, Niesler TR. Regression adjusted colocalisation colour mapping (RACC): A novel biological visual analysis method for qualitative colocalisation analysis of 3D fluorescence micrographs. Plos ONE. 2019 Oct 29;14(11): e0225141. Link Link
3 Neethling A, Engelbrecht L, Loos B, Kinnear C, Theart R, Abrahams S, Niesler T, Mellick GD, Williams M, Bardien S. Wild-type and mutant (G2019S) leucine-rich repeat kinase 2 (LRRK2) associate with subunits of the translocase of outer mitochondrial membrane (TOM) complex. Experimental Cell Research. 2018 Dec 28. Link
2 Theart RP, Loos B, Powrie YS, Niesler TR. Improved region of interest selection and colocalization analysis in three-dimensional fluorescence microscopy samples using virtual reality. Plos ONE. 2018 Aug 29;13(8): e0201965. Link Video
1 Theart RP, Loos B, Niesler TR. Virtual reality assisted microscopy data visualization and colocalization analysis. BMC Bioinformatics. 2017 Feb;18(2):64. Link Video

Conference Publications

# Paper Print (DOI) Pre-P (Open) Data/
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1 Deyzel M, Theart RP. Skeleton-Based Action Recognition on Strength and Conditioning Exercises. InProceedings of the IEEE/CVF Conference on Computer Vision and Pattern Recognition 2023 (pp. 5168-5177). Link

Patents

Miscellaneous